Phentermine – Adipex-P


What Is Phentermine (Adipex-P)?

Phentermine is the generic form of the brand-name drugs Adipex-P, Suprenza, and Ionamin, which are used for weight loss.

Phentermine decreases appetite and stimulates the body to burn calories more quickly.

Fastin, a former brand name for phentermine, is no longer available in the United States.

Phentermine is a controlled substance, and should only be taken for a short period of time (no more than three weeks).

People taking phentermine should also cut back on calories and try to exercise while taking the drug.

Phentermine is generally prescribed for people who are very overweight with a body-mass index (BMI) greater than 30.

Phentermine makes the nervous system operate in a kind of “fight-or-flight” mode by stimulating brain chemicals known as neurotransmitters.

It was first approved as a diet drug in 1959, and has been on the market in various forms since then.

In the late 1990s, the Food and Drug Administration (FDA) removed a combination diet drug known as fen-phen (for fenfluramine and phentermine) from the market because of evidence that it could damage heart valves.

Since then, the FDA has approved phentermine combined with different drugs.




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Uses of Phentermine

This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.

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Phentermine Adipex-P ‘High’ and Abuse

Phentermine is a stimulant that is habit-forming and used by some people in dangerously large doses to get high.

If you take it for too long, or take more of it than your doctor prescribes, you may become dependent and develop depression or fatigue when you stop taking it.

Phentermine Adipex-P Warnings

The FDA warns that you should only take phentermine for a maximum of a few weeks, and you should not take it with any other weight-loss drugs or herbal treatments.

People who have any of the following should not take phentermine:

  • Severe hardening of the arteries (atherosclerosis)
  • Heart disease
  • Moderate-to-severe high blood pressure
  • Glaucoma
  • If you are feeling very irritable, jittery, or agitated
  • If you have taken a monoamine oxidase inhibitor (MAOI) such as Nardil or tranylcypromine within the past 14 days
  • Diabetes
  • Overactive thyroid
  • History of drug abuse

Your doctor will want to monitor you closely if you take phentermine and have high blood pressure, problems with your heart valves, reduced kidney function, or are elderly.

Phentermine may cause increased blood pressure in the lungs or problems with the valves in your heart.

You should stop taking phentermine right away and tell your doctor if you notice any of the following symptoms:

  • Difficulty breathing
  • Chest pain
  • Feeling faint
  • Swelling in the feet, ankles, and lower legs

Phentermine may lose its effect after you have been taking it for a while, and when that happens, you should stop taking it.

Pregnancy and Phentermine Adipex-P

Phentermine falls under the FDA’s Pregnancy Category C, which means harm to an unborn baby is possible.

You should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.

You should also alert your physician if you are breastfeeding or plan to breastfeed.

It’s not recommended that women breastfeed while taking phentermine.

Phentermine Adipex-P Side Effects

If you experience any of the following more common side effects of phentermine and they don’t go away or become sever, call your doctor or seek emergency medical care:

  • Dry mouth
  • Constipation
  • Mild headache
  • Diarrhea
  • Itching

Serious Side Effects and Reactions

Phentermine may cause serious side effects. You should tell your doctor right away if you experience any of the following:

  • Chest, arm, or jaw pain
  • Very fast heartbeat
  • Swelling in your feet or legs
  • High blood pressure
  • Shortness of breath
  • Dizziness
  • Shaking or trembling
  • Weakness or problems walking
  • Unpleasant or bad taste in the mouth
  • Itching, skin redness, or rash

Tell your doctor if you experience any of the following, because they could be signs of a serious reaction to phentermine:

  • Upset stomach
  • Changes in sexual desire or inability to get an erection
  • Tirelessness or inability to sleep
  • Problems with thinking
  • Unusual feelings or behaviors, such as jitteriness, extra sensitivity, an unusual sense of well-being or invincibility (euphoria), or unease or dissatisfaction (dysphoria)
  • Hallucinations (hearing or seeing things that aren’t there)
  • Bad taste in the mouth
  • Become dependent on or addicted to phentermine

If you stop taking phentermine after taking it for a long period, you might experience symptoms of withdrawal, such as depression or fatigue.

Phentermine Adipex-P Interactions

It’s always important to tell your doctor and pharmacist about all of your treatments, including over-the-counter (OTC) medications; vitamins, nutritional shakes, protein powders, and other supplements; herbal treatments or other alternative medicines; and any illegal or recreational drugs.

It’s always important to tell your doctor and pharmacist about all of your treatments, including over-the-counter (OTC) medications; vitamins, nutritional shakes, protein powders, and other supplements; herbal treatments or other alternative medicines; and any illegal or recreational drugs.

The following drugs interact with phentermine:

  • Isoproterenol
  • Dopamine
  • Ephedrine
  • Epinephrine
  • Norepinephrine (Levophed)
  • Linezolid (Zyvox)
  • Phenylephrine injection
  • Venlafaxine (Effexor, Effexor XR)

Phentermine and Alcohol

You should not consume alcohol or any other medication that dulls the nervous system while taking phentermine, since it can work against the desired effects of phentermine.

Combining phentermine and alcohol may increase your risk of experiencing side effects of the drug, including stomach problems and diarrhea.

Phentermine and Other Interactions

  • Amphetamine (Adderall)
  • Benzphetamine (Didrex, Regimex)
  • Dexmethylphenidate (Focalin XR, Focalin)
  • Dextroamphetamine (Dexadrine)
  • Diethylpropion
  • Isocarboxazid (Marplan)
  • Lisdexamfetamine (Vyvanse)
  • Methamphetamine (Desoxyn)
  • Methylphenidate (Concerta, Metadate CD, Methylin, Ritalin)
  • Phendimetrazine (Bontril, Bontril PDM)
  • Henelzine (Nardil)
  • Procarbazine (Matulane)
  • Selegeline transdermal patches (Emsam)
  • Sibutramine (Meridia)
  • Tranylcypromine (Parnate)

Phentermine Adipex-P Dosage

It should be prescribed at the lowest possible dosage and may depend on your condition and body weight.

Different brands of phentermine should be taken differently, but in general, phentermine is best taken on an empty stomach one hour before eating breakfast, or two hours after eating breakfast, to prevent it from interfering with your sleep.

It’s important to avoid taking it before 6:00 p.m. because it can cause problems with sleeping.

The orally disintegrating Suprenza brand can be taken with or without food.

Do not swallow the Suprenza tablet, but rather let the tablet to dissolve on your tongue.

Phentermine Overdose

If you suspect an overdose, you should contact a poison-control center or emergency room immediately.

You can get in touch with a poison-control center at (800) 222-1222.

Missed Dose of Phentermine

If you miss a dose of phentermine, try to take it as soon as you remember.

If it’s almost time for the next dose, skip the missed dose and take your next dose at the regular time.

Don’t take two doses of the medication at the same time.

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